Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201735 | 0.80 | HRH1 (0.50) | TAAR1 | |
| SCHEMBL6280516 | 0.79 | RIPK1 (0.67) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL5413664 | 0.78 | TAAR1 (0.52) | RIPK1AOC3TAAR1TRPA1 | |
| Lithium SCHEMBL30777534 | 0.77 | RIPK1 (0.64) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL5213988 | 0.77 | RIPK1 (0.64) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL10599884 | 0.77 | TSHR (0.42) | AOC3TAAR1RAB9A | |
| SCHEMBL27586527 | 0.76 | RIPK1 (0.57) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL27586660 | 0.76 | RIPK1 (0.57) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL2243710 | 0.76 | RIPK1 (0.57) | RIPK1AOC3TAAR1TRPA1 | |
| SCHEMBL1532968 | 0.75 | SLC6A4 (0.38) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |