Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549967 | 0.94 | ALDH1A1 (0.36) | ALDH1A1ALOX15TSHRCHRNB4CHRNA3 | |
| SCHEMBL2543009 | 0.86 | ALDH1A1 (0.36) | ALDH1A1ALOX15TSHRCHRNB4CHRNA3 | |
| SCHEMBL28911580 | 0.76 | HRH3 (0.46) | ALDH1A1HRH2HRH3 | |
| SCHEMBL2013779 | 0.74 | ALDH1A1 (0.33) | ALDH1A1ALOX15TSHRCHRNB4CHRNA3 | |
| SCHEMBL4607832 | 0.74 | ALDH1A1 (0.33) | ALDH1A1ALOX15TSHRCHRNB4CHRNA3 | |
| SCHEMBL695560 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP1A2 | |
| SCHEMBL15758247 | 0.72 | IGF1R (0.46) | ALDH1A1ALOX15 | |
| SCHEMBL16817775 | 0.71 | MAPT (0.41) | ALDH1A1ALOX15TSHR | |
| SCHEMBL5534036 | 0.70 | HRH2 (0.41) | ALDH1A1CHRNB4CHRNA3HRH2HRH3 | |
| SCHEMBL7700085 | 0.70 | CHRNB4 (0.41) | ALDH1A1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170056313-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | CREATIVE NAIL DESIGN, INC. (US) | 2017-03-02 | — | — | US | disclosed |
| EP-1794233-A1 | POSS CONTAINING COSMETIC COMPOSITIONS HAVING IMPROVED WEAR AND/OR PLIABILITY AND METHODS OF MAKING IMPROVED COSMETIC COMPOSITIONS | L'OREAL (FR) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006031781-A1 | POSS CONTAINING COSMETIC COMPOSITIONS HAVING IMPROVED WEAR AND/OR PLIABILITY AND METHODS OF MAKING IMPROVED COSMETIC COMPOSITIONS | L'OREAL (FR) | 2006-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170056313-A1 | NAIL COATINGS HAVING ENHANCED ADHESION | POLR1C, PIK3C3, NACA | ALDH1A1 1567/4885ALOX15 2390/4885TSHR 4023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.