Sugi Predict

Sugi Predict / Compounds / SCHEMBL548601

SCHEMBL548601

SCHEMBL548601

O=Cc1ccc(C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.57
▸ LMNA P02545 3/20 0.57
▸ GAA P10253 2/20 0.49
▸ NPC1 O15118 2/20 0.49
▸ EPHX2 P34913 6/20 0.47
▸ MEN1 O00255 3/20 0.47
▸ KMT2A Q03164 3/20 0.47
▸ POLB P06746 2/20 0.47
▸ GFER P55789 1/20 0.47
▸ RAB9A P51151 2/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ MAPT P10636 1/20 0.42
▸ GRIN2D O15399 1/20 0.41
▸ GRIN3B O60391 1/20 0.41
▸ GRIN1 Q05586 1/20 0.41
▸ GRIN2A Q12879 1/20 0.41
▸ GRIN2B Q13224 1/20 0.41
▸ GRIN2C Q14957 1/20 0.41
▸ GRIN3A Q8TCU5 1/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28326184 0.98 ALDH1A1 (0.55) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL21753170 0.90 MEN1 (0.49) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL13286725 0.85 GRIN2D (0.44) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL2763437 0.82 LMNA (0.77) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL547745 0.82 ALDH1A1 (0.37) ALDH1A1LMNAGAANPC1GRIN2D
SCHEMBL8289283 0.80 ALDH1A1 (0.38) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL10012164 0.80 ALDH1A1 (0.57) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL2776531 0.80 ALDH1A1 (0.57) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL677047 0.80 ALDH1A1 (0.57) ALDH1A1LMNAGAANPC1EPHX2
SCHEMBL6620334 0.79 MEN1 (0.55) ALDH1A1LMNAGAANPC1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119069699-A Conductive carbon material and preparation method thereof, pole piece, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-12-03 — — CN claimed
CN-112480305-B Polymer type flame retardant and preparation method thereof 广东知塑新材料有限公司 2023-05-09 — — CN claimed
CN-115193273-B Covalent organic framework composite membrane, preparation method thereof and reaction vessel 北京石墨烯技术研究院有限公司 2022-12-02 — — CN claimed
CN-115193273-A Covalent organic framework composite membrane, preparation method thereof and reaction vessel 北京石墨烯技术研究院有限公司 2022-10-18 — — CN claimed
CN-105601813-B A kind of modified polyvinyl carbazoles high-molecular luminous material and preparation method thereof 广东工业大学 2017-12-22 — — CN claimed
CN-105601813-A Modified polyvinyl carbazole high-polymer luminescent material and preparation method thereof UNIV GUANGDONG TECHNOLOGY 2016-05-25 — — CN claimed
CN-103755541-A Chalcone derivative as well as preparation method and application thereof UNIV XIAMEN 2014-04-30 — — CN claimed
CN-116606296-B Electronic transmission material phenanthroline derivative and synthesis and application method thereof 西安欧得光电材料有限公司 2025-03-04 — — CN disclosed
CN-119069699-A Conductive carbon material and preparation method thereof, pole piece, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-12-03 — — CN disclosed
CN-116606296-A Electronic transmission material phenanthroline derivative and synthesis and application method thereof 西安欧得光电材料有限公司 2023-08-18 — — CN disclosed
CN-116178645-A Non-penetrating covalent organic frameworks, methods of making and using the same 中国石油化工股份有限公司 2023-05-30 — — CN disclosed
CN-112480305-B Polymer type flame retardant and preparation method thereof 广东知塑新材料有限公司 2023-05-09 — — CN disclosed
CN-115193273-B Covalent organic framework composite membrane, preparation method thereof and reaction vessel 北京石墨烯技术研究院有限公司 2022-12-02 — — CN disclosed
EP-2080750-A1 RADIATION-SENSITIVE COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2009-07-22 — — EP disclosed
EP-1670757-B1 PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS LILLY CO ELI (US) 2009-05-06 — — EP disclosed
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors ELI LILLY AND COMPANY 2007-03-22 — — US disclosed
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors ELI LILLY AND COMPANY 2007-03-22 — — US disclosed
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors ELI LILLY AND COMPANY 2007-03-22 — — US disclosed
EP-1670757-A1 PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS ELI LILLY AND COMPANY (US) 2006-06-21 — — EP disclosed
WO-2005040110-A1 PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS ELI LILLY AND COMPANY (US) 2005-05-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066573-A1 Pyrrole and pyrazole derivatives as potentiators of glutamate receptors GRIN1, GRIN3A, GRIK5 ALDH1A1 2211/4885LMNA 4874/4885GAA 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.