Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486064 | 1.00 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL5474315 | 0.82 | HSD11B1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL5474311 | 0.82 | HSD11B1 (0.68) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL5477436 | 0.81 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL5470754 | 0.81 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL5470757 | 0.81 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL5475174 | 0.81 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL5478093 | 0.81 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL5479946 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2APOLBHSD11B1 | |
| SCHEMBL3170967 | 0.79 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112000-A1 | Chemical compounds | ASTRAZENECA R&D ALDERLEY (GB) | 2007-05-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112000-A1 | Chemical compounds | HSD11B1, CYP11B1, HSD11B2 | ALDH1A1 68/4885SMN1; SMN2 4541/4885MEN1 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.