Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790647 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL5307075 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL5307972 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL1133830 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL27969814 | 0.73 | ALDH1A1 (0.51) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL15077477 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HPGDHTTSMN1; SMN2HTR1A | |
| SCHEMBL5448429 | 0.68 | CA2 (0.36) | ALDH1A1HPGDHTR1AADRA1DADRA1A | |
| SCHEMBL5450391 | 0.68 | CA2 (0.36) | ALDH1A1HPGDHTR1AADRA1DADRA1A | |
| SCHEMBL5446871 | 0.68 | CA2 (0.36) | ALDH1A1HPGDHTR1AADRA1DADRA1A | |
| SCHEMBL4977214 | 0.68 | TLR2 (0.43) | ALDH1A1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007506661-A | — | — | 2007-03-22 | — | — | JP | claimed |
| EP-1638540-A2 | PYRAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS PLATELET AGGREGATION INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2006-03-29 | — | — | EP | claimed |
| WO-2005000281-A2 | PYRAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS PLATELET AGGREGATION INHIBITORS | ACTELION PHARMACEUTICALS LTD. (CH) | 2005-01-06 | — | — | WO | claimed |