Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.36 |
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133830 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL15077475 | 0.82 | MAPK14 (0.35) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL3446578 | 0.80 | APP (0.40) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL1133799 | 0.80 | HTR1A (0.36) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL1133796 | 0.80 | HTR1A (0.36) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL13552003 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDSMN1; SMN2MAPK14ADRA1D | |
| SCHEMBL5307075 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL4790647 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL5307972 | 0.78 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2HTTMAPK14 | |
| SCHEMBL13117490 | 0.75 | MAPK14 (0.40) | ALDH1A1HPGDSMN1; SMN2MAPK14ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530452-B2 | Tricyclic boron compounds for antimicrobial therapy | MICURX PHARMACEUTICALS, INC. (KY) | 2013-09-10 | — | — | US | disclosed |
| US-8530452-B2 | Tricyclic boron compounds for antimicrobial therapy | MICURX PHARMACEUTICALS, INC. (KY) | 2013-09-10 | — | — | US | disclosed |
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | US | disclosed |
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | MICURX PHARMACEUTICALS, INC. (KY) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165411-A1 | TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY | TBCA, TBCB, BTD | ALDH1A1 4409/4885HPGD 4390/4885SMN1; SMN2 1879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.