SCHEMBL5486175

SCHEMBL5486175

CCc1ccc2c(c1CC)=c1ccccc1=2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
TP53 P04637 1/20 0.31
MGLL Q99685 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27991554 0.76 KDM4E (0.36)
SCHEMBL7006718 0.76 GABRA1 (0.46) GABRA1GABRB2TP53MGLL
SCHEMBL10783900 0.76 GABRA1 (0.46) GABRA1GABRB2TP53MGLL
SCHEMBL29619533 0.71 GABRA1 (0.41) GABRA1GABRB2TP53MGLLHTT
SCHEMBL166573 0.71 GABRA1 (0.41) GABRA1GABRB2TP53MGLLHTT
SCHEMBL6557581 0.71 LIPG (0.45) TP53HTT
SCHEMBL19838166 0.69 GABRA1 (0.40) GABRA1GABRB2MGLL
Ammonia Solution, Strong SCHEMBL27539208 0.69 GABRA1 (0.39) GABRA1GABRB2TP53MGLLHTT
SCHEMBL9000240 0.67 GABRA1 (0.52) GABRA1GABRB2TP53MGLL
SCHEMBL14692720 0.67 GABRA1 (0.35) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070012569-A1 Cationic electrodeposition coating composition NIPPON PAINT CO., LTD. (JP) 2007-01-18 US disclosed