SCHEMBL7006718

SCHEMBL7006718

CCc1cccc2c1=c1ccccc1=2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
MGLL Q99685 1/20 0.38
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TP53 P04637 1/20 0.35
CLCN2 P51788 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34
MAOA P21397 1/20 0.34
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10783900 1.00 GABRA1 (0.46) GABRA1GABRB2MGLLMAPTNPSR1
SCHEMBL28157092 0.90 GABRA1 (0.41) GABRA1GABRB2MGLLMAPTNPSR1
Hydrochloric Acid SCHEMBL28237585 0.88 GABRA1 (0.40) GABRA1GABRB2MGLLMAPTNPSR1
SCHEMBL19838166 0.83 GABRA1 (0.40) GABRA1GABRB2MGLLLMNACRHBP
SCHEMBL27554686 0.79 LIPG (0.43)
Naphthalene SCHEMBL27028568 0.78 CSNK2A2 (0.37) GABRA1GABRB2MAPTMEN1KMT2A
SCHEMBL27792377 0.78 NPC1 (0.33) GABRA1GABRB2MAPTL3MBTL1LMNA
SCHEMBL5486175 0.76 GABRA1 (0.32) GABRA1GABRB2MGLLTP53
SCHEMBL11136888 0.76 LIPG (0.53)
SCHEMBL28390493 0.76 LIPG (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-05-21 US claimed
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US claimed
US-8865322-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US claimed
EP-0847228-B1 Material for organoelectroluminescence device and use thereof TOYO INK MFG CO (JP) 2003-04-16 EP disclosed
EP-1191020-A2 Material for organic electroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 2002-03-27 EP disclosed
US-6245449-B1 LIGHT EMITTER LAYERS OR ORGANIC COMPOUNDS, THIN LAYERS AND ELECTRODES, ANODES AND CATHODES TOYO INK MANUFACTURING CO., LTD. (JP) 2001-06-12 US disclosed
US-6150042-A ELECTROLUMINESCENCE DEVICE WITH HOLE INJECTING MATERIAL HAVING GOOD DURABILITY BEING A TRIPHENYLENE STRUCTURE OF GIVEN FORMULA HAVING MULTIPLE ETHER, SULFIDE, AND/OR AMINE SUBSTITUTIONS TOYO INK MANUFACTURING CO., LTD. (JP) 2000-11-21 US disclosed
EP-0847228-A2 Material for organoelectroluminescence device and use thereof TOYO INK MANUFACTURING CO., LTD. (JP) 1998-06-10 EP disclosed
US-5382687-A Electrography HITACHI CHEMICAL COMPANY LTD. (JP) 1995-01-17 US disclosed
EP-0448389-B1 Enamine derivatives and their use in electrophotographic member HITACHI CHEMICAL CO LTD (JP) 1994-12-14 EP disclosed
US-5272030-A Electrophotographic member comprising enamine derivatives HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-12-21 US disclosed
EP-0448389-A1 Enamine derivatives and their use in electrophotographic member Hitachi Chemical Co., Ltd. (JP) 1991-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10297765-B2 Aromatic amine derivative and organic electroluminescent device using the same DDT, TYR, DDC GABRA1 2753/4885GABRB2 2434/4885MGLL 2454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.