Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486241 | 1.00 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CPPARGCARM1 | |
| SCHEMBL10989713 | 0.79 | PPARG (0.42) | ADRA2AADRA2BADRA2CPPARGCARM1 | |
| SCHEMBL4797438 | 0.75 | HTR1D (0.40) | CARM1PRMT6PRMT8ATMLMNA | |
| SCHEMBL5478633 | 0.75 | SLC6A4 (0.50) | ADRA2AADRA2BADRA2CPPARGLMNA | |
| SCHEMBL5478630 | 0.75 | SLC6A4 (0.50) | ADRA2AADRA2BADRA2CPPARGLMNA | |
| Hydrochloric Acid SCHEMBL5476841 | 0.74 | SLC6A4 (0.49) | ADRA2AADRA2BADRA2CPPARGLMNA | |
| Hydrochloric Acid SCHEMBL5476834 | 0.74 | SLC6A4 (0.49) | ADRA2AADRA2BADRA2CPPARGLMNA | |
| Hydrochloric Acid SCHEMBL5476840 | 0.74 | SLC6A4 (0.49) | ADRA2AADRA2BADRA2CPPARGLMNA | |
| SCHEMBL5474792 | 0.71 | TMEM97 (0.45) | ATMKDM4EALDH1A1SIGMAR1TMEM97 | |
| SCHEMBL5474795 | 0.71 | TMEM97 (0.45) | ATMKDM4EALDH1A1SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ADRB3, HTR3C, SLC6A2 | ADRA2A 40/4885ADRA2B 27/4885ADRA2C 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.