Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595049 | 0.96 | IDH1 (0.40) | PRKAG1PRKAA1PRKAB1IDH1TNKS | |
| SCHEMBL5174949 | 0.82 | PIK3CA (0.38) | IDH1TNKSMAP2K1EGLN2DGAT1 | |
| SCHEMBL13167913 | 0.82 | HSD11B1 (0.47) | TNKSF10CMA1NAAAKDM1A | |
| SCHEMBL13167926 | 0.78 | HSP90AA1 (0.39) | IDH1TNKSEGLN2DGAT1CCNC | |
| SCHEMBL5800891 | 0.78 | PIK3CA (0.43) | IDH1TNKSEGLN2CCNCCDK8 | |
| SCHEMBL21723494 | 0.78 | SLC6A2 (0.48) | CMA1ADRB1ALDH1A1 | |
| SCHEMBL30980936 | 0.78 | DRD2 (0.40) | IDH1F10CMA1DRD2DRD3 | |
| SCHEMBL15499081 | 0.75 | PKM (0.48) | CMA1CCNCCDK8ALDH1A1HSD17B10 | |
| SCHEMBL8349969 | 0.74 | BPTF (0.43) | TNKSCMA1EGLN2DGAT1CCNC | |
| SCHEMBL26298453 | 0.74 | EGLN2 (0.40) | IDH1TNKSCMA1MAP2K1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787684-B1 | New couplers | HENKEL AG & CO KGAA (DE) | 2016-01-20 | — | — | EP | claimed |
| EP-1787684-A2 | New couplers | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-23 | — | — | EP | claimed |
| EP-1787684-B1 | New couplers | HENKEL AG & CO KGAA (DE) | 2016-01-20 | — | — | EP | disclosed |
| EP-1787684-A2 | New couplers | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-23 | — | — | EP | disclosed |
| EP-1787684-A2 | New couplers | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-23 | — | — | EP | disclosed |