SCHEMBL5486771

SCHEMBL5486771

Nc1ccc(C=O)c(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
LMNA P02545 3/20 0.41
KMT2A Q03164 3/20 0.41
THRB P10828 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
BLM P54132 1/20 0.41
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
FGR P09769 1/20 0.38
PIM1 P11309 1/20 0.38
MAOA P21397 1/20 0.38
ADORA2A P29274 1/20 0.38
CSNK1A1 P48729 1/20 0.38
CSNK1D P48730 1/20 0.38
DYRK1A Q13627 1/20 0.38
HIPK2 Q9H2X6 1/20 0.38
CSNK1G1 Q9HCP0 1/20 0.38
ALDH1A1 P00352 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15251911 0.84 LMNA (0.46) NPC1RAB9ALMNAKMT2ATHRB
SCHEMBL28035372 0.81 ALDH1A1 (0.39) NPC1RAB9ALMNAKMT2AMEN1
SCHEMBL27770212 0.81 CYP2A6 (0.39) NPC1RAB9AKMT2ATHRBTDP1
SCHEMBL27703192 0.80 ALDH1A1 (0.39) LMNAKMT2ATDP1MEN1MAPT
SCHEMBL28247742 0.80 ALDH1A1 (0.48) NPC1RAB9ALMNAKMT2ATHRB
SCHEMBL29546125 0.80 HSD17B10 (0.50) LMNAKMT2ATHRBTDP1MEN1
SCHEMBL25014 0.80 HSD17B10 (0.50) LMNAKMT2ATHRBTDP1MEN1
Water SCHEMBL27969596 0.78 HSD17B10 (0.48) LMNAKMT2ATHRBTDP1MEN1
SCHEMBL28770475 0.78 LMNA (0.42) NPC1RAB9ALMNAKMT2ATHRB
SCHEMBL2569625 0.77 MAOB (0.45) NPC1RAB9ALMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788861-B Iridium (III) complex and preparation method and application thereof 山东普力强生物科技有限公司 2023-08-01 CN claimed
CN-1882307-A Method for dyeing fibres containing keratine HENKEL KGAA (DE) 2006-12-20 CN claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
CN-116891494-A Preparation method and application of viscosity-sensitive heterocyclic compound 三峡大学 2023-10-17 CN disclosed
CN-113788861-B Iridium (III) complex and preparation method and application thereof 山东普力强生物科技有限公司 2023-08-01 CN disclosed
US-10633470-B2 Method of producing a conjugated diene polymer, a modified conjugated diene polymer, and a vinyl cis-polybutadiene composition UBE INDUSTRIES, LTD. (JP) 2020-04-28 US disclosed
US-10508163-B2 Conjugated diene polymer and modified conjugated diene polymer produced using the same, rubber composition for tire, and rubber composition for rubber belt UBE INDUSTRIES, LTD. (JP) 2019-12-17 US disclosed
US-20190256628-A1 Method of Producing a Conjugated Diene Polymer, a Modified Conjugated Diene Polymer, and a Vinyl Cis-Polybutadiene Composition UBE INDUSTRIES, LTD. (JP) 2019-08-22 US disclosed
CN-106604935-B Method for producing terminal-modified conjugated diene polymer, rubber composition, and tire 株式会社普利司通 2019-02-22 CN disclosed
CN-109153737-A The manufacturing method of terminal-modified conjugated diolefin polymer, rubber composition, rubber product and terminal-modified conjugated diolefin polymer 株式会社普利司通 2019-01-04 CN disclosed
US-20180079844-A1 \"Conjugated Diene Polymer and Modified Conjugated Diene Polymer Produced Using the Same, Rubber Composition for Tire, And Rubber Composition for Rubber Belt\ UBE INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
US-20020185634-A1 Two-photon or higher-order absorbing optical materials and methods of use CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-12-12 US disclosed
US-6267913-B1 IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-07-31 US disclosed
CN-1298623-A Organic electroluminescent device IDEMITSU KOSAN CO (JP) 2001-06-06 CN disclosed
CN-1286890-A Organic electroluminescent device and method for manufacturing the same IDEMITSU KOSAN CO (JP) 2001-03-07 CN disclosed
WO-1998021521-A9 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INST OF TECHN (US) 2000-03-02 WO disclosed
EP-0951661-A4 1999-11-17 EP disclosed
EP-0951661-A1 PROCESS AND COMPOSITION FOR GENERATING ACID POLAROID CORPORATION (US) 1999-10-27 EP disclosed
WO-1998024000-A1 PROCESS AND COMPOSITION FOR GENERATING ACID POLAROID CORPORATION (US) 1998-06-04 WO disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed