SCHEMBL27770212

SCHEMBL27770212

Cc1ccc(-c2c(N)ccc(C=O)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 5/20 0.36
KMT2A Q03164 4/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 3/20 0.36
NPC1 O15118 2/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
MAPT P10636 1/20 0.36
PTK2B Q14289 1/20 0.36
DUSP3 P51452 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
THRB P10828 2/20 0.34
TP53 P04637 1/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4248242 0.82 TDP1 (0.48) ALDH1A1SMN1; SMN2KMT2ARAB9AKDM4E
SCHEMBL5486771 0.81 NPC1 (0.42) CYP2A6ALDH1A1KMT2ARAB9AKDM4E
SCHEMBL7935194 0.77 ALDH1A1 (0.54) CYP2A6ALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL7215674 0.76 CYP2A6 (0.40) CYP2A6ALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL5568778 0.75 NFE2L2 (0.42) ALDH1A1SMN1; SMN2RAB9AKDM4ENPC1
SCHEMBL353048 0.74 TDP1 (0.41) ALDH1A1SMN1; SMN2KMT2ARAB9AKDM4E
SCHEMBL22769863 0.74 TSHR (0.39) CYP2A6ALDH1A1SMN1; SMN2KMT2AKDM4E
SCHEMBL5220216 0.72 CA2 (0.40) ALDH1A1SMN1; SMN2KMT2ARAB9AKDM4E
SCHEMBL5573183 0.71 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2KMT2ARAB9AKDM4E
SCHEMBL3384426 0.70 TDP1 (0.52) CYP2A6ALDH1A1SMN1; SMN2RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101429131-B Synthesis of N,N-di(4-methyl phenyl)-4-(2, 2-diphenylethyllene)aniline BEIJING ODYSSEY CHEMICALS CO LTD 2011-03-23 CN disclosed
CN-101429131-A Synthesis of N,N-di(4-methyl phenyl)-4-(2, 2-diphenylethyllene)aniline BEIJING ODYSSEY CHEMICALS CO L (CN) 2009-05-13 CN disclosed