Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | TST | Q16762 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483456 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL14340029 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL7609465 | 0.98 | ALDH1A1 (0.48) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL14264692 | 0.95 | HSD17B10 (0.51) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL17684937 | 0.93 | CA2 (0.44) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL11049506 | 0.84 | HSD17B10 (0.50) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL14267367 | 0.84 | HSD17B10 (0.53) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL5490593 | 0.84 | HSD17B10 (0.53) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL2947258 | 0.82 | THRA (0.33) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL2952443 | 0.82 | THRA (0.34) | HSD17B10ALDH1A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |