Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4525487 | 0.80 | ABCG2 (0.30) | ABCG2 | |
| SCHEMBL1818063 | 0.74 | ABCG2 (0.51) | ABCG2 | |
| Hydrochloric Acid SCHEMBL4458466 | 0.70 | ABCG2 (0.66) | ABCG2 | |
| Hydrochloric Acid SCHEMBL3270111 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4525483 | 0.69 | ABCG2 (0.53) | ABCG2 | |
| SCHEMBL4448186 | 0.69 | ABCG2 (0.64) | ABCG2 | |
| SCHEMBL1820361 | 0.69 | ABCG2 (0.68) | ABCG2 | |
| SCHEMBL4313626 | 0.69 | ABCG2 (0.68) | ABCG2 | |
| SCHEMBL1899423 | 0.69 | ABCG2 (0.68) | ABCG2 | |
| SCHEMBL2955387 | 0.68 | ABCG2 (0.58) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196147-B2 | Olefin polymerization process with improved operability and polymer properties | EQUISTAR CHEMICALS, LP (US) | 2007-03-27 | — | — | US | disclosed |
| WO-2007005112-A1 | OLEFIN POLYMERIZATION PROCESS WITH IMPROVED OPERABILITY AND POLYMER PROPERTIES | EQUISTAR CHEMICALS, LP (US) | 2007-01-11 | — | — | WO | disclosed |
| US-20070004881-A1 | Olefin polymerization process with improved operability and polymer properties | EQUISTAR CHEMICALS, LP | 2007-01-04 | — | — | US | disclosed |
| US-6908972-B2 | Method for making polyolefins | EQUISTAR CHEMICALS, LP (US) | 2005-06-21 | — | — | US | disclosed |
| US-20030195306-A1 | Method for making polyolefins | EQUISTAR CHEMICALS, LP | 2003-10-16 | — | — | US | disclosed |