Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14853295 | 0.89 | MEN1 (0.64) | MEN1KMT2ASMN1; SMN2MMEACE | |
| SCHEMBL5550287 | 0.87 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11394858 | 0.84 | ALDH1A1 (0.59) | MEN1KMT2ASMN1; SMN2MMEACE | |
| SCHEMBL8243069 | 0.83 | ALDH1A1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL5902551 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9515306 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL10791327 | 0.79 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2TAAR1MME | |
| SCHEMBL5270163 | 0.79 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2TAAR1MME | |
| SCHEMBL14209990 | 0.79 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2TAAR1MME | |
| SCHEMBL4681925 | 0.78 | MEN1 (0.86) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007525670-A | — | — | 2007-09-06 | — | — | JP | claimed |
| EP-1718971-A2 | SYSTEM AND METHOD FOR REAL-TIME DIAGNOSIS, TREATMENT, AND THERAPEUTIC DRUG MONITORING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2006-11-08 | — | — | EP | claimed |
| WO-2005098429-A2 | SYSTEM AND METHOD FOR REAL-TIME DIAGNOSIS, TREATMENT, AND THERAPEUTIC DRUG MONITORING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-0511003-B1 | Superactive GRF analogs | LILLY CO ELI (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0511003-A1 | Superactive GRF analogs | ELI LILLY AND COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |