Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19592390 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TSHRSMN1; SMN2HPGDTP53 | |
| SCHEMBL12125177 | 0.82 | ALDH1A1 (0.64) | ALDH1A1TSHRSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL7815830 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2HPGDTP53 | |
| SCHEMBL5486970 | 0.79 | MEN1 (0.57) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL11645404 | 0.79 | MTNR1B (0.63) | ALDH1A1TSHRSMN1; SMN2HPGDMAPT | |
| SCHEMBL28229345 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRSMN1; SMN2HPGDTP53 | |
| SCHEMBL8298315 | 0.78 | MTNR1B (0.81) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2308107 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL29410396 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL28712746 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5118681-A | Bactericides | ROHM AND HAAS COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |