Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765987 | 0.85 | TAAR1 (0.36) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL30997335 | 0.85 | TAAR1 (0.36) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL5490687 | 0.85 | TAAR1 (0.50) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL6740216 | 0.80 | TAAR1 (0.71) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL3224942 | 0.77 | ALDH1A1 (0.36) | TAAR1KMT2A | |
| SCHEMBL5486703 | 0.76 | IDO1 (0.52) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL6673171 | 0.76 | TAAR1 (0.54) | TAAR1KMT2ADAO | |
| SCHEMBL6655794 | 0.75 | TAAR1 (0.48) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL575128 | 0.73 | TAAR1 (0.62) | TAAR1IDO1PNMTSLC6A2SLC6A4 | |
| SCHEMBL1822278 | 0.73 | TAAR1 (0.62) | TAAR1IDO1PNMTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-4575559-A | Process for preparing certain sulfophenethylsiloxanes | BASF WYANDOTTE CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |