Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.47 |
| ▸ | TUBB | P07437 | 3/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015727 | 0.88 | NQO2 (0.61) | NQO2TUBB1CYP1A1TUBB4ATUBB | |
| SCHEMBL5492437 | 0.84 | TRPA1 (0.44) | NQO2TUBB1CYP1A1TUBB4ATUBB | |
| SCHEMBL16168067 | 0.83 | NQO2 (0.77) | NQO2TUBB1CYP1A1TUBB4ATUBB | |
| SCHEMBL13898796 | 0.81 | TUBB1 (0.46) | NQO2TUBB1NFE2L2ALDH1A1MAPT | |
| SCHEMBL14363441 | 0.80 | CYP1A1 (0.73) | NQO2TUBB1CYP1A1TUBB4ATUBB | |
| SCHEMBL13050008 | 0.77 | APP (0.44) | NQO2TUBB1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13978801 | 0.77 | TUBB1 (0.49) | NQO2TUBB1NFE2L2ALDH1A1MAPT | |
| SCHEMBL10015732 | 0.77 | TUBB1 (0.49) | NQO2TUBB1NFE2L2ALDH1A1MAPT | |
| SCHEMBL10047112 | 0.76 | NQO2 (0.67) | NQO2TUBB1CYP1A1TUBB4ATUBB | |
| SCHEMBL18085345 | 0.76 | TUBB1 (0.49) | NQO2TUBB1CYP1A1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | claimed |
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | PNMT, CYP1A1, TERT | NQO2 164/4885TUBB1 3033/4885CYP1A1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.