Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413159 | 0.95 | FFAR4 (0.55) | P2RX7FFAR4PLGPLAUALOX5 | |
| SCHEMBL7367613 | 0.89 | KMO (0.52) | P2RX7FFAR4KMOKDM4EALDH1A1 | |
| SCHEMBL4327022 | 0.86 | HDAC1 (0.53) | P2RX7KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4335712 | 0.83 | TNF (0.51) | P2RX7FFAR4 | |
| SCHEMBL17242289 | 0.82 | P2RX7 (0.56) | P2RX7FFAR4PLGPLAUKDM4E | |
| SCHEMBL16824128 | 0.81 | P2RX7 (0.55) | P2RX7FFAR4PLGPLAUACLY | |
| SCHEMBL3465527 | 0.81 | KMT2A (0.55) | P2RX7FFAR4KDM4EALDH1A1TSHR | |
| SCHEMBL17242442 | 0.81 | P2RX7 (0.54) | P2RX7FFAR4PLGPLAUKDM4E | |
| SCHEMBL4334807 | 0.81 | P2RX7 (0.52) | P2RX7FFAR4PLGPLAUKDM4E | |
| SCHEMBL10593438 | 0.80 | KMO (0.62) | PLGPLAUALOX5EPHX2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134169-A2 | INDOLE, BENZIMIDAZOLE, AND BENZOLACTAM BORONIC ACID COMPOUNDS, ANALOGS THEREOF AND METHODS OF USE THEREOF | NUADA, LLC (US) | 2007-11-22 | — | — | WO | disclosed |