SCHEMBL5487486

SCHEMBL5487486

C=COc1ccccc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.38
GRM4 Q14833 3/20 0.37
ADRA2B P18089 2/20 0.35
ADRA2C P18825 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 4/20 0.33
RAB9A P51151 4/20 0.33
HPGD P15428 3/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
LY96 Q9Y6Y9 1/20 0.33
MAPT P10636 2/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5492190 0.82 ADRA2B (0.30) ADRA2BADRA2C
SCHEMBL3113317 0.82 ADRA2B (0.43) ADRA2BADRA2CLMNAHPGDKMT2A
SCHEMBL29592755 0.82 ADRA2B (0.43) ADRA2BADRA2CLMNAHPGDKMT2A
SCHEMBL25386322 0.79
SCHEMBL1191551 0.76 GRM4 (0.41) HTR7GRM4L3MBTL1LMNARAB9A
SCHEMBL6574818 0.76 HTR7 (0.38) HTR7GRM4ADRA2BADRA2CL3MBTL1
SCHEMBL1223374 0.76 HTR7 (0.42) HTR7GRM4ADRA2BADRA2CL3MBTL1
SCHEMBL2730818 0.76 HTR7 (0.39) HTR7GRM4ADRA2BADRA2CL3MBTL1
SCHEMBL17063054 0.75 ADRA2B (0.37) HTR7ADRA2BADRA2CALDH1A1
SCHEMBL264175 0.74 PKM (0.50) L3MBTL1LMNARAB9AKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100395668-C Compensating developer and developing method CANON KK (JP) 2008-06-18 CN disclosed
CN-100363842-C Image forming apparatus with a toner supply device CANON KK (JP) 2008-01-23 CN disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-7030170-B2 Photosensitive resin composition, dry film, and workpiece using the same MITSUI CHEMICALS, INC. (JP) 2006-04-18 US disclosed
CN-1550932-A Image forming apparatus with a toner supply device ������������ʽ���� 2004-12-01 CN disclosed
US-20030176528-A1 Photosensitive resin composition, dry film, and workpiece using the same MITSUI CHEMICALS, INC. (JP) 2003-09-18 US disclosed
CN-1384401-A Compensating developer and developing method CANON KK (JP) 2002-12-11 CN disclosed