Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.71 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10540728 | 0.84 | AHR (0.70) | AHRCYP1B1HSD17B10HPGDTSHR | |
| Polychlorinated Biphenyl 126 SCHEMBL6535350 | 0.84 | AHR (1.00) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| Polychlorinated Biphenyl 126 SCHEMBL308662 | 0.84 | AHR (1.00) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| Polychlorinated Biphenyl 126 SCHEMBL6942325 | 0.84 | AHR (1.00) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| SCHEMBL7906570 | 0.79 | AHR (0.70) | AHRCYP1B1HSD17B10HPGDTSHR | |
| SCHEMBL8773713 | 0.79 | AHR (0.70) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| SCHEMBL137915 | 0.78 | AHR (1.00) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| SCHEMBL29769221 | 0.78 | AHR (1.00) | AHRCYP1B1HSD17B10TSHRALDH1A1 | |
| SCHEMBL4456281 | 0.77 | ESR2 (0.65) | AHRCYP1B1HSD17B10HPGDTSHR | |
| SCHEMBL5487549 | 0.77 | HSD17B10 (0.67) | AHRCYP1B1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802798-A1 | METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS | CHIRON CORPORATION (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995022992-A1 | METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS | CHIRON CORPORATION (US) | 1995-08-31 | — | — | WO | disclosed |