Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495156 | 0.89 | MAPK14 (0.49) | MAPK14SMODDR2SMN1; SMN2TSHR | |
| SCHEMBL5489952 | 0.88 | MAPK14 (0.48) | MAPK14SMODDR2SMN1; SMN2TSHR | |
| SCHEMBL5481692 | 0.72 | MAPK14 (0.77) | MAPK14SMODDR2MAPK13MAPK12 | |
| SCHEMBL5489948 | 0.71 | MAPK14 (0.48) | MAPK14SMOSMN1; SMN2TSHRNPC1 | |
| SCHEMBL10130385 | 0.70 | DDR2 (0.54) | MAPK14SMODDR2MAPK12 | |
| SCHEMBL5489954 | 0.69 | GRM5 (0.44) | MAPK14SMOSMN1; SMN2TSHRNPC1 | |
| SCHEMBL10130489 | 0.69 | DDR2 (0.53) | MAPK14SMODDR2SMN1; SMN2TSHR | |
| SCHEMBL5480980 | 0.69 | MAPK14 (0.46) | MAPK14SMOSMN1; SMN2TSHRNPC1 | |
| SCHEMBL12764365 | 0.69 | SMN1; SMN2 (0.58) | MAPK14SMOSMN1; SMN2TSHRNPC1 | |
| SCHEMBL6483771 | 0.68 | MAPK14 (0.54) | MAPK14SMOSMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |