Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489952 | 0.99 | MAPK14 (0.48) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5488208 | 0.89 | MAPK14 (0.49) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5489954 | 0.76 | GRM5 (0.44) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5489948 | 0.73 | MAPK14 (0.48) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5480980 | 0.71 | MAPK14 (0.46) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12764365 | 0.70 | SMN1; SMN2 (0.58) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5481692 | 0.70 | MAPK14 (0.77) | MAPK14SMODDR2 | |
| SCHEMBL6483771 | 0.70 | MAPK14 (0.54) | MAPK14SMOSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10130385 | 0.70 | DDR2 (0.54) | MAPK14SMODDR2SRC | |
| SCHEMBL12764388 | 0.70 | SMN1; SMN2 (0.57) | MAPK14SMOSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |