Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495153 | 0.85 | ALDH1A1 (0.45) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5480980 | 0.74 | MAPK14 (0.46) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5489952 | 0.74 | MAPK14 (0.48) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5495156 | 0.73 | MAPK14 (0.49) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5488200 | 0.73 | ALDH1A1 (0.39) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL4551331 | 0.72 | MAPK14 (0.71) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL12764388 | 0.71 | SMN1; SMN2 (0.57) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5489954 | 0.71 | GRM5 (0.44) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL5488208 | 0.71 | MAPK14 (0.49) | MAPK14SMOALDH1A1MAPTRAB9A | |
| SCHEMBL4551323 | 0.71 | MAPK14 (0.72) | MAPK14SMOALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |