Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.77 |
| ▸ | SMO | Q99835 | 4/20 | 0.66 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411010 | 0.86 | MAPK14 (0.73) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5481697 | 0.85 | MAPK14 (0.71) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL14534470 | 0.81 | MAPK14 (0.67) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4551323 | 0.79 | MAPK14 (0.72) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4551331 | 0.79 | MAPK14 (0.71) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5481690 | 0.78 | MAPK14 (0.62) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL5490044 | 0.77 | MAPK14 (0.74) | MAPK14SMO | |
| SCHEMBL6486278 | 0.77 | MAPK14 (1.00) | MAPK14SMO | |
| SCHEMBL7809441 | 0.76 | MAPK14 (0.77) | MAPK14SMOMAPK13MAPK12MAPK11 | |
| SCHEMBL4418530 | 0.74 | MAPK14 (0.61) | MAPK14SMOMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |