SCHEMBL5488235

SCHEMBL5488235

CCCP(=O)(OCC)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AOX1 Q06278 1/20 0.70
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ACHE P22303 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
CCNT1 O60563 1/20 0.47
CDK9 P50750 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KCNH2 Q12809 1/20 0.46
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.44
POLB P06746 1/20 0.43
NR1I2 O75469 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777194 0.89 AOX1 (0.66) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL5488445 0.87 MEN1 (0.65) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL28693406 0.86 AOX1 (0.62) AOX1NPSR1ALDH1A1
SCHEMBL27925108 0.85 AOX1 (0.66) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL2515116 0.85 AOX1 (0.66) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL16260353 0.84 AOX1 (0.52) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL779739 0.84 AOX1 (0.64) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL5491426 0.84 MEN1 (0.51) AOX1MEN1KMT2AL3MBTL1
SCHEMBL5488227 0.83 AOX1 (0.50) AOX1MEN1KMT2AACHEL3MBTL1
SCHEMBL14809495 0.83 AOX1 (0.51) AOX1MEN1KMT2AACHEL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070087270-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SOLUTION SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-7169511-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2007-01-30 US disclosed
US-20050014071-A1 Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-01-20 US disclosed
US-6583177-B2 Amidinophenol derivatives as leukotriene B4 (LTB4)antagonists, phospholipase A2 inhibitors, and trypsin inhibitors. ONO PHARMACEUTICAL CO., LTD. (JP) 2003-06-24 US disclosed
US-20020128315-A1 Leukotriene B4 antagonist compounds and method for treatment NAKAI HISAO (JP) 2002-09-12 US disclosed
US-6262114-B1 NOVEL AMIDINOPHENOL DERIVATIVES; INHIBITORS OF PHOSPHOLIPASE A2 AND/OR TRYPSIN ONO PHARMACEUTICAL CO., LTD. (JP) 2001-07-17 US disclosed
EP-0703216-B1 Amidinophenol derivatives as protease inhibitors ONO PHARMACEUTICAL CO (JP) 1999-04-07 EP disclosed
EP-0703216-A1 Amidinophenol derivatives as protease inhibitors ONO PHARMACEUTICAL CO., LTD. (JP) 1996-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128315-A1 Leukotriene B4 antagonist compounds and method for treatment LTB4R2, LTB4R, LTA4H AOX1 417/4885MEN1 4125/4885KMT2A 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.