SCHEMBL5488260

SCHEMBL5488260

CCCCCCNC(=O)c1cc(O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 1.00
EGFR P00533 2/20 0.71
ALOX5 P09917 2/20 0.71
PTGS2 P35354 2/20 0.71
SYK P43405 1/20 0.71
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
MAOB P27338 1/20 0.54
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
TRPV1 Q8NER1 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
CDK1 P06493 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626446 1.00 NAAA (1.00) NAAAEGFRALOX5PTGS2SYK
SCHEMBL9785906 1.00 NAAA (1.00) NAAAEGFRALOX5PTGS2SYK
SCHEMBL11212195 1.00 NAAA (1.00) NAAAEGFRALOX5PTGS2SYK
SCHEMBL10883907 0.88 NAAA (0.78) NAAAEGFRALOX5PTGS2SYK
SCHEMBL12919722 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK
SCHEMBL17774851 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK
SCHEMBL17774885 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK
SCHEMBL15887753 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK
SCHEMBL19077958 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK
SCHEMBL26096811 0.85 NAAA (0.74) NAAAEGFRALOX5PTGS2SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9149530-B2 Compositions and methods for enhancing active agent absorption NEXUS PHARMA, INC. (US) 2015-10-06 US disclosed
US-8426466-B2 Compositions and methods for enhancing active agent absorption NEXUS PHARMA, INC. (US) 2013-04-23 US disclosed
US-20070269494-A1 Compositions and methods for enhancing active agent absorption NEXUS PHARMA, INC. 2007-11-22 US disclosed
US-20070269500-A1 Compositions and methods for enhancing active agent absorption NEXUS PHARMA, INC. 2007-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070269494-A1 Compositions and methods for enhancing active agent absorption FABP2, SLC10A2, SI NAAA 440/4885EGFR 2675/4885ALOX5 242/4885
US-20070269500-A1 Compositions and methods for enhancing active agent absorption FABP2, SLC10A2, SI NAAA 440/4885EGFR 2675/4885ALOX5 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.