Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTR5A | P47898 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22901475 | 0.81 | PDK2 (0.36) | PDK2PDK4ALDH1A1HTR5APOLB | |
| SCHEMBL24519732 | 0.69 | PGR (0.36) | PDK2PDK4ALDH1A1HTR5APOLB | |
| SCHEMBL12629401 | 0.67 | PDK2 (0.41) | PDK2PDK4ALDH1A1HTR5ABRPF1 | |
| SCHEMBL1316216 | 0.67 | PDK2 (0.41) | PDK2PDK4ALDH1A1HTR5ABRPF1 | |
| Iodide SCHEMBL7543439 | 0.65 | PDK2 (0.39) | PDK2PDK4ALDH1A1HTR5ABRPF1 | |
| SCHEMBL14677972 | 0.64 | ALDH1A1 (0.34) | ALDH1A1POLBBRPF1CREBBPLMNA | |
| SCHEMBL12900962 | 0.63 | PDK2 (0.34) | PDK2PDK4ALDH1A1HTR5ASUV39H1 | |
| SCHEMBL18862019 | 0.63 | ALDH1A1 (0.55) | ALDH1A1HTR5APOLBBRPF1CREBBP | |
| SCHEMBL15587865 | 0.63 | PDK2 (0.41) | PDK2PDK4ALDH1A1HTR5AMEN1 | |
| SCHEMBL7759529 | 0.63 | BRD4 (0.44) | PDK2PDK4ALDH1A1HTR5APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218534-B1 | NOVEL ENZYMES AND METABOLITES INVOLVED IN SKATOLE METABOLISM | UNIV GUELPH (CA) | 2007-07-04 | — | — | EP | disclosed |
| US-7202035-B2 | Genetic markers for skatole metabolism | UNIVERSITY OF GUELPH (CA) | 2007-04-10 | — | — | US | disclosed |
| US-20070031837-A1 | Genetic markers for skatole metabolism | UNIVERSITY OF GUELPH (CA) | 2007-02-08 | — | — | US | disclosed |
| US-20060150263-A1 | Novel enzymes and metabolites involved in skatole metabolism | UNIVERSITY OF GUELPH (CA) | 2006-07-06 | — | — | US | disclosed |
| EP-1623004-A2 | GENETIC MARKERS FOR SKATOLE METABOLISM | University of Guelph (CA) | 2006-02-08 | — | — | EP | disclosed |
| WO-2005030924-A2 | GENETIC MARKERS FOR SKATOLE METABOLISM | UNIVERSITY OF GUELPH (CA) | 2005-04-07 | — | — | WO | disclosed |
| US-20030228614-A1 | Genetic markers for skatole metabolism | UNIVERSITY OF GUELPH (CA) | 2003-12-11 | — | — | US | disclosed |
| US-20020197663-A1 | Novel enzymes and metabolites involved in skatole metabolism | UNIVERSITY OF GUELPH (CA) | 2002-12-26 | — | — | US | disclosed |
| US-6448028-B1 | METHODS TO IDENTIFY AND REDUCE BOAR TAINT, DUE TO HIGH LEVELS OF EITHER THE 16-ANDROSTENE STEROIDS OR SKATOLE IN FAT, BY MEASURING LEVELS OF METABOLITES | UNIVERSITY OF GUELPH (CA) | 2002-09-10 | — | — | US | disclosed |
| EP-1218534-A2 | NOVEL ENZYMES AND METABOLITES INVOLVED IN SKATOLE METABOLISM | University of Guelph (CA) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023601-A2 | NOVEL ENZYMES AND METABOLITES INVOLVED IN SKATOLE METABOLISM | UNIVERSITY OF GUELPH (CA) | 2001-04-05 | — | — | WO | disclosed |