Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614522 | 0.83 | CYP3A4 (0.43) | CYP3A4IDO1HTTSMN1; SMN2POLB | |
| SCHEMBL5488564 | 0.78 | IDO1 (0.56) | CYP3A4IDO1HTTSMN1; SMN2CYP1A2 | |
| SCHEMBL15093979 | 0.78 | CYP3A4 (0.48) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL5487357 | 0.78 | PYCR1 (0.44) | CYP3A4P2RX7CYP1A2CYP2C9MAPK1 | |
| SCHEMBL5645934 | 0.77 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL27628619 | 0.76 | CYP3A4 (0.43) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL171203 | 0.76 | CYP3A4 (0.43) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL998743 | 0.76 | CYP3A4 (0.43) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL193074 | 0.74 | CYP3A4 (0.46) | HDAC3HDAC1HDAC2HDAC6CYP3A4 | |
| SCHEMBL1096478 | 0.74 | PSEN1 (0.42) | HDAC3HDAC1HDAC2HDAC6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |