Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482845 | 0.83 | HDAC3 (0.40) | CYP3A4IDO1HTTSMN1; SMN2SLC6A4 | |
| SCHEMBL5490741 | 0.78 | POLB (0.34) | CYP3A4SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL8418306 | 0.76 | CYP3A4 (0.48) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL31459834 | 0.76 | CYP3A4 (0.48) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL9861809 | 0.76 | CYP3A4 (0.48) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL12167672 | 0.74 | CYP3A4 (0.46) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL5488564 | 0.74 | IDO1 (0.56) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL6588336 | 0.74 | CYP3A4 (0.46) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL14363075 | 0.74 | IDO1 (0.56) | CYP3A4IDO1HTTSMN1; SMN2LMNA | |
| SCHEMBL30995430 | 0.74 | CYP3A4 (0.46) | CYP3A4IDO1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |