Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 3/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL5490443 | 0.84 | LMNA (0.47) | TDP1GABBR2GABBR1FDPSLAP3 | |
| E968 SCHEMBL5490881 | 0.84 | GABBR2 (0.39) | TDP1GABBR2GABBR1FDPSLAP3 | |
| Propylene Glycol SCHEMBL4710370 | 0.83 | TDP1 (0.59) | TDP1TSHRFDPSLAP3MMP2 | |
| SCHEMBL5488328 | 0.83 | GABBR2 (0.35) | TDP1GABBR2GABBR1FDPSLAP3 | |
| 1,3-Butanediol SCHEMBL5493726 | 0.83 | GABBR2 (0.35) | TDP1GABBR2GABBR1TSHRFDPS | |
| Propylene Glycol SCHEMBL6852797 | 0.83 | TDP1 (0.67) | TDP1GABBR2GABBR1TSHRFDPS | |
| Propylene Glycol SCHEMBL315221 | 0.83 | TDP1 (0.67) | TDP1GABBR2GABBR1TSHRFDPS | |
| Propylene Glycol SCHEMBL22285873 | 0.83 | TDP1 (0.67) | TDP1GABBR2GABBR1TSHRFDPS | |
| Propylene Glycol SCHEMBL7862899 | 0.80 | TDP1 (0.62) | TDP1GABBR2GABBR1TSHRFDPS | |
| Propylene Glycol SCHEMBL29186483 | 0.80 | TDP1 (0.62) | TDP1GABBR2GABBR1TSHRFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070087270-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SOLUTION SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-04-19 | — | — | US | disclosed |
| US-7169511-B2 | Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-01-30 | — | — | US | disclosed |
| EP-1555711-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY CONTAINING THE SAME | Mitsubishi Chemical Corporation (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-20050014071-A1 | Nonaqueous electrolyte solution and nonaqueous electrolyte solution secondary battery employing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2005-01-20 | — | — | US | disclosed |