⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62327 | 0.81 | — | — | |
| SCHEMBL58209 | 0.77 | — | — | |
| SCHEMBL127281 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL29140292 | 0.75 | — | — | |
| SCHEMBL14480559 | 0.72 | — | — | |
| SCHEMBL5217866 | 0.72 | HPGD (0.39) | — | |
| SCHEMBL2194083 | 0.69 | BACE1 (0.41) | — | |
| SCHEMBL182716 | 0.69 | — | — | |
| SCHEMBL930755 | 0.69 | GABRA1 (0.48) | — | |
| SCHEMBL930329 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2803 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117887016-A | Polybiphenyl phenolic resin and preparation method and application thereof | 同宇新材料(广东)股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| US-20230233536-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | QURETECH BIO AB (SE) | 2023-07-27 | — | — | US | claimed |
| US-20210401815-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | WASHINGTON UNIVERSITY | 2021-12-30 | — | — | US | claimed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | claimed |
| CN-107974080-B | Polyamide moulding compositions and multilayer structures made therefrom | EMS专利股份公司 | 2021-07-20 | — | — | CN | claimed |
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-31 | — | — | US | claimed |
| EP-3740493-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2020-11-25 | — | — | EP | claimed |
| CN-111601810-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-08-28 | — | — | CN | claimed |
| EP-3638681-A1 | RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA | Quretech Bio AB (SE) | 2020-04-22 | — | — | EP | claimed |
| CN-110799513-A | Ring-fused thiazolo-2-pyridones, method for the production thereof and use thereof for treating and/or preventing diseases which involve gram-positive bacteria | 快尔生物技术公司 | 2020-02-14 | — | — | CN | claimed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-0880542-A2 | SUBSTRATES AND INHIBITORS FOR CYSTEINE PROTEASE ICH-1 | BASF AG (US) | 1998-12-02 | — | — | EP | claimed |
| WO-1997027220-A2 | SUBSTRATES AND INHIBITORS FOR CYSTEINE PROTEASE ICH-1 | BASF AG (US) | 1997-07-31 | — | — | WO | claimed |
| CN-1141298-A | Pyrimidine-fused heterocyclic compound anti-cancer agents | PFIZER (US) | 1997-01-29 | — | — | CN | claimed |
| US-5321040-A | Pesticidal 1-aryl-5-(substituted N-cinnamylideneimino) pyrazoles | RHONE-POULENC INC. (US) | 1994-06-14 | — | — | US | claimed |
| EP-0231497-B1 | Silicone resist materials containing polysiloxanes | TOSHIBA KK (JP) | 1994-03-02 | — | — | EP | claimed |
| US-5236938-A | Pesticidal 1-aryl-5-(substituted alkylideneimino)pyrazoles | RHONE-POULENC INC. (US) | 1993-08-17 | — | — | US | claimed |
| CN-1066265-A | 1-aryl-5-(substituted alkylideneimino) Insecticidal pyrazolines | RHONE POULENC AGROCHIMIE (FR) | 1992-11-18 | — | — | CN | claimed |
| EP-0511845-A1 | Pesticidal 1-aryl-5-(substituted alkylideneimino)-pyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1992-11-04 | — | — | EP | claimed |
| EP-0231497-A1 | Silicone resist materials containing polysiloxanes | KABUSHIKI KAISHA TOSHIBA (JP) | 1987-08-12 | — | — | EP | claimed |