Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952684 | 0.86 | NPC1 (0.48) | METAP2METAP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9725329 | 0.86 | METAP2 (0.53) | METAP2METAP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20550741 | 0.82 | ALOX5 (0.64) | METAP2METAP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20550742 | 0.80 | ALOX5 (0.53) | METAP2METAP1P2RY6ALDH1A1KDM4E | |
| SCHEMBL12071689 | 0.77 | SMN1; SMN2 (0.61) | METAP2METAP1ALDH1A1KDM4EHSD17B10 | |
| Fuberidazole SCHEMBL29603252 | 0.76 | ALOX5 (0.65) | P2RY6ALDH1A1KDM4EHSD17B10HPGD | |
| Fuberidazole SCHEMBL8817074 | 0.76 | ALOX5 (0.65) | P2RY6ALDH1A1KDM4EHSD17B10HPGD | |
| Fuberidazole SCHEMBL23174 | 0.76 | ALOX5 (0.65) | P2RY6ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL3503448 | 0.73 | KDR (0.69) | METAP2METAP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2312932 | 0.73 | NPC1 (0.45) | METAP2METAP1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1837024-A2 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-09-26 | — | — | EP | disclosed |
| US-7183286-B2 | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-02-27 | — | — | US | disclosed |
| EP-1399163-A2 | COMPOUNDS, METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS (BVDV) INFECTION AND HEPATITIS C VIRUS (HCV) INFECTION | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002055025-A2 | COMPOUNDS, METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS (BVDV) INFECTION AND HEPATITIS C VIRUS (HCV) INFECTION | UNIV NORTH CAROLINA (US) | 2002-07-18 | — | — | WO | disclosed |