Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952684 | 0.89 | NPC1 (0.48) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL12071689 | 0.87 | SMN1; SMN2 (0.61) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL5488987 | 0.86 | METAP2 (0.47) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL2312932 | 0.82 | NPC1 (0.45) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL10070465 | 0.81 | KDM4E (0.50) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL2317573 | 0.80 | RAB9A (0.43) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL20677815 | 0.80 | NPC1 (0.75) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3503448 | 0.80 | KDR (0.69) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL3501986 | 0.80 | KDR (0.69) | METAP2METAP1NPC1RAB9AALDH1A1 | |
| SCHEMBL3337258 | 0.80 | NPC1 (0.66) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |