Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NAT1 | P18440 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262806 | 0.83 | PTGES2 (0.40) | PTGES2CA1CA2CA6CA9 | |
| SCHEMBL29866197 | 0.81 | NAT1 (0.43) | PTGES2NAT1ADORA2AADORA1MAOB | |
| SCHEMBL1080972 | 0.77 | CA2 (0.61) | CA1CA2CA6CA9CA4 | |
| SCHEMBL27200652 | 0.76 | PRMT6 (0.46) | PTGES2CA1CA2CA4CA12 | |
| SCHEMBL10626109 | 0.76 | NAT1 (0.43) | PTGES2NAT1ADORA2AADORA1MEN1 | |
| SCHEMBL27200649 | 0.75 | PTGES2 (0.43) | PTGES2NAT1 | |
| SCHEMBL31019010 | 0.75 | CA12 (0.46) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL8347239 | 0.75 | CA2 (0.58) | CA1CA2CA6CA9CA4 | |
| SCHEMBL22435633 | 0.74 | NAT1 (0.37) | NAT1MAOBPOLBTAAR1KDM4E | |
| SCHEMBL3262803 | 0.74 | PTGES2 (0.40) | PTGES2CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183320-B2 | Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents | ELI LILLY AND COMPANY (US) | 2007-02-27 | — | — | US | disclosed |