Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 5/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489312 | 0.75 | PTGES2 (0.46) | CA12CA1CA2CA9PTGES2 | |
| SCHEMBL27200649 | 0.73 | PTGES2 (0.43) | PTGES2NAT1ALOX5APFEN1 | |
| SCHEMBL3262806 | 0.70 | PTGES2 (0.40) | CA12CA1CA2CA9PTGES2 | |
| SCHEMBL31019009 | 0.68 | PTGES2 (0.40) | CA1CA2PTGES2NAT1PIK3R1 | |
| SCHEMBL731096 | 0.67 | CA2 (0.48) | CA12CA1CA2CA9PTGES2 | |
| SCHEMBL14602504 | 0.67 | MAPT (0.42) | CA12CA1CA2CA9TAAR1 | |
| SCHEMBL10720270 | 0.66 | CA12 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL5188633 | 0.65 | CA1 (0.46) | CA12CA1CA2CA9PTGES2 | |
| SCHEMBL27200652 | 0.64 | PRMT6 (0.46) | CA12CA1CA2PTGES2NAT1 | |
| SCHEMBL4266775 | 0.64 | MAPT (0.41) | TAAR1MAOBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262812-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | SHANGHAI LEADO PHARMATECH CO. LTD. (CN) | 2024-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262812-A1 | N-SUBSTITUTED PHENYLSULFONAMIDE COMPOUND AND USE THEREOF | TRPV1, TRPA1, TRPV5 | CA12 4325/4885CA1 3003/4885CA2 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.