Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713472 | 0.89 | ALDH1A1 (0.57) | ALDH1A1NPSR1MAPTCA1CA2 | |
| SCHEMBL10285030 | 0.83 | ALDH1A1 (0.68) | ALDH1A1NPSR1MAPTCA1CA2 | |
| SCHEMBL3477633 | 0.83 | IDO1 (0.61) | ALDH1A1NPSR1IDO1LMNANPC1 | |
| SCHEMBL19214926 | 0.83 | NPSR1 (0.69) | ALDH1A1NPSR1MAPTCA1CA2 | |
| SCHEMBL163727 | 0.82 | MEP1B (0.59) | ALDH1A1NPSR1CA1CA2LMNA | |
| SCHEMBL28707304 | 0.82 | NPSR1 (0.56) | ALDH1A1NPSR1MAPTLMNAKMT2A | |
| SCHEMBL28039061 | 0.80 | CA2 (0.64) | ALDH1A1NPSR1CA1CA2LMNA | |
| SCHEMBL1429021 | 0.80 | CA1 (0.68) | ALDH1A1NPSR1MAPTCA1CA2 | |
| SCHEMBL14744565 | 0.79 | ALDH1A1 (0.66) | ALDH1A1NPSR1MAPTCA1CA2 | |
| SCHEMBL8076558 | 0.79 | ALDH1A1 (1.00) | ALDH1A1NPSR1MAPTFFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005670-A2 | NATURAL AND SYNTHETIC SULFOXIDE, SELENONE AND SELENOXIDE ANALOGS AND POLYMER CONJUGATED FORMS THEREOF FOR THE MODULATION OF ANGIOGENESIS | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2007-01-11 | — | — | WO | claimed |