Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492796 | 1.00 | RAB9A (0.52) | RAB9ATRPV1NPC1MAOBHPGD | |
| SCHEMBL5493874 | 0.94 | KDM4E (0.47) | RAB9ATRPV1NPC1MAOBHPGD | |
| SCHEMBL5815295 | 0.92 | TRPV1 (0.50) | RAB9ATRPV1NPC1MAOBHPGD | |
| SCHEMBL5497203 | 0.92 | TRPV1 (0.50) | RAB9ATRPV1NPC1MAOBHPGD | |
| SCHEMBL5493158 | 0.87 | RAB9A (0.56) | RAB9ATRPV1NPC1MAOBHPGD | |
| SCHEMBL4270755 | 0.87 | CYP1A2 (0.57) | HPGDKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5489818 | 0.87 | CYP1A2 (0.57) | HPGDKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5492850 | 0.87 | CYP1A2 (0.57) | HPGDKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL4270751 | 0.87 | CYP1A2 (0.57) | HPGDKDM4EALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29359315 | 0.86 | TRPV1 (0.67) | RAB9ATRPV1NPC1MAOBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073860-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-07-07 | — | — | US | disclosed |
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | US | disclosed |
| US-8580752-B2 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTITIC AND INDUSTRIAL RESEARCH (IN) | 2013-11-12 | — | — | US | disclosed |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073595-A1 | AROMATIC AMIDES AS POTENTIATORS OF BIOEFFICACY OF ANTI-INFECTIVE DRUGS | DDC, APEH, AADAC | RAB9A 2057/4885TRPV1 1550/4885NPC1 3733/4885 |
| US-20070004645-A1 | Aromatic amides as potentiators of bioefficacy of anti-infective drugs | DDC, APEH, AADAC | RAB9A 2057/4885TRPV1 1550/4885NPC1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.