Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431704 | 0.88 | CCNB2 (0.49) | PI4KAPI4K2BPI4K2API4KBCNR1 | |
| SCHEMBL5470970 | 0.83 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL2681825 | 0.81 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL5479505 | 0.80 | CCNB2 (0.55) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL28496042 | 0.79 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBMAPT | |
| SCHEMBL20551317 | 0.78 | CCNE2 (0.45) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL5472887 | 0.77 | CCNB2 (0.52) | PI4KAPI4K2BPI4K2API4KBTRPV1 | |
| SCHEMBL31061395 | 0.75 | EGFR (0.59) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL5486053 | 0.74 | CCNB2 (0.52) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL5490074 | 0.73 | ALDH1A1 (0.53) | TRPV1KDM4EHTTHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197559-A1 | Aryl substituted purine analogues | NEUROGEN CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070197559-A1 | Aryl substituted purine analogues | NEUROGEN CORPORATION | 2007-08-23 | — | — | US | disclosed |
| US-20070197559-A1 | Aryl substituted purine analogues | NEUROGEN CORPORATION | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197559-A1 | Aryl substituted purine analogues | ADORA2A, GART, P2RX7 | PI4KA 3012/4885PI4K2B 3297/4885PI4K2A 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.