Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5482943 | 0.81 | TACR1 (0.47) | KMT2AMEN1ALDH1A1SGMS2L3MBTL1 | |
| Carbamic Acid SCHEMBL5481170 | 0.81 | KDM4E (0.65) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| Carbamic Acid SCHEMBL5490536 | 0.79 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL5335651 | 0.77 | LMNA (0.57) | KMT2AMEN1ALDH1A1SGMS2L3MBTL1 | |
| SCHEMBL1566337 | 0.76 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| Carbamic Acid SCHEMBL5490727 | 0.75 | KMT2A (0.53) | KMT2AMEN1L3MBTL1KDM4ESMN1; SMN2 | |
| Carbamic Acid SCHEMBL5485774 | 0.74 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL5305401 | 0.74 | LMNA (0.60) | KMT2AMEN1ALDH1A1SGMS2L3MBTL1 | |
| SCHEMBL1412911 | 0.73 | HTR1A (0.59) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| Carbamic Acid SCHEMBL5490629 | 0.73 | SCN3A (0.61) | KMT2AKDM4ESMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |