Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551789 | 0.86 | PDE4B (0.37) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL4551561 | 0.86 | RAB9A (0.38) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL4565880 | 0.82 | MAPK14 (0.44) | PDE4BMAPK14DGAT1RAF1BRAF | |
| SCHEMBL5490933 | 0.81 | PDE4B (0.41) | PDE4BMAPK14CYP1A2LCKKDR | |
| SCHEMBL4551650 | 0.81 | PDE4B (0.40) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL5484353 | 0.79 | RAF1 (0.48) | MAPK14RAF1BRAF | |
| SCHEMBL4551611 | 0.78 | CSF1R (0.43) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL5487365 | 0.74 | MAPK14 (0.46) | PDE4BMAPK14RAF1BRAF | |
| SCHEMBL4551942 | 0.74 | FAAH (0.31) | — | |
| SCHEMBL5490162 | 0.74 | TNK2 (0.44) | MAPK14LCKKDRTEKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |