Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551650 | 0.99 | PDE4B (0.40) | PDE4BMAPK7SETD2MAPK14LCK | |
| SCHEMBL4551789 | 0.90 | PDE4B (0.37) | PDE4BMAPK7SETD2MAPK14LCK | |
| SCHEMBL4551561 | 0.90 | RAB9A (0.38) | PDE4BMAPK7SETD2MAPK14LCK | |
| SCHEMBL4551611 | 0.87 | CSF1R (0.43) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL5487365 | 0.87 | MAPK14 (0.46) | PDE4BMAPK14RAF1BRAF | |
| SCHEMBL4551481 | 0.86 | SETD2 (0.34) | PDE4BMAPK7SETD2MAPK14KDR | |
| SCHEMBL4551536 | 0.85 | SMN1; SMN2 (0.33) | PDE4BMAPK7SETD2MAPK14KDR | |
| SCHEMBL4551772 | 0.85 | PDE4B (0.43) | PDE4BMAPK14LCKKDRTEK | |
| SCHEMBL4551615 | 0.81 | PDE4B (0.45) | PDE4BMAPK14MAPTRAB9ADGAT1 | |
| SCHEMBL5490159 | 0.81 | PDE4B (0.40) | PDE4BMAPK14LCKKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |