Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491232 | 0.76 | GSTP1 (0.61) | GSTP1MAPTTP53THRB | |
| SCHEMBL10552053 | 0.72 | GSTP1 (0.58) | GSTP1MAPT | |
| SCHEMBL10824824 | 0.71 | GSTP1 (0.68) | GSTP1MAPTTP53 | |
| SCHEMBL3132479 | 0.70 | — | — | |
| SCHEMBL743966 | 0.70 | — | — | |
| SCHEMBL13983098 | 0.69 | GSTP1 (0.49) | GSTP1MAPTTP53HIF1A | |
| SCHEMBL8545969 | 0.68 | GSTP1 (0.44) | GSTP1MAPTTP53 | |
| SCHEMBL1237584 | 0.67 | GSTP1 (0.46) | GSTP1MAPTTP53HIF1A | |
| SCHEMBL3369781 | 0.67 | MAPT (0.37) | GSTP1MAPTTP53HIF1ATHRB | |
| SCHEMBL9374330 | 0.67 | GSTP1 (0.38) | GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287672-A1 | Macromolecular Gsh-Activiated Glyoxylase I Inhibitors | MARYLAND, UNIVERSITY OF, BALTIMORE COUNTY | 2007-12-13 | — | — | US | disclosed |
| WO-2005115338-A2 | MACROMOLECULAR GSH-ACTIVATED GLYOXYLASE I INHIBITORS | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287672-A1 | Macromolecular Gsh-Activiated Glyoxylase I Inhibitors | GLO1, GGT1, GSTA1 | GSTP1 4/4885MAPT 4635/4885TP53 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.