SCHEMBL5490455

SCHEMBL5490455

Nc1c(C=Cc2ccccc2)ccc(-c2ccnnn2)c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.36
CYP19A1 P11511 2/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
KDM4E B2RXH2 4/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GRM4 Q14833 4/20 0.34
HDAC6 Q9UBN7 1/20 0.34
SLC2A1 P11166 1/20 0.34
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
TRPA1 O75762 1/20 0.33
NFE2L2 Q16236 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11499911 0.89 DHFR (0.35) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL30785927 0.89 DHFR (0.39) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL8612737 0.89 DHFR (0.39) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL30677882 0.89 DHFR (0.39) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL9774338 0.84 DHFR (0.36) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL3113210 0.83 SLC2A1 (0.34) DHFRCYP19A1MAOAMAOBKDM4E
SCHEMBL1536251 0.81 NFE2L2 (0.41) DHFRMAOBKDM4ENPC1RAB9A
SCHEMBL1136448 0.81 NFE2L2 (0.41) DHFRMAOBKDM4ENPC1RAB9A
SCHEMBL1012568 0.76 NFE2L2 (0.37) DHFRMAOBKDM4EMEN1KMT2A
SCHEMBL7558871 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9211821-A None JP disclosed
CN-1863900-B Color tone changing composition CIBA SPEC CHEM CORP 2011-01-26 CN disclosed
US-7225926-B2 Cleaning container for photographic treatment composition FUJIFILM CORPORATION (JP) 2007-06-05 US disclosed
CN-1863900-A Color tone changing composition CIBA SC HOLDING AG (CH) 2006-11-15 CN disclosed
CN-1177259-C Single part color photographic prosessing slurry 富士亨特感光化学品公司 2004-11-24 CN disclosed
EP-1070279-B1 Single part color photographic processing slurry FUJI HUNT PHOTO CHEM (US) 2004-11-03 EP disclosed
US-6526998-B2 Method of cleaning container for photographic treatment composition and apparatus therefor FUJI PHOTO FILM CO., LTD. (JP) 2003-03-04 US disclosed
US-6491047-B2 Method of cleaning container for photographic treatment composition and apparatus therefor FUJI PHOTO FILM CO., LTD. (JP) 2002-12-10 US disclosed
EP-0800111-B1 Photographic processing composition in slurry form FUJI PHOTO FILM CO LTD (JP) 2002-07-24 EP disclosed
EP-1149147-A1 FLUORESCENT WHITENING AGENT, ITS PREPARATION AND USE Ciba SC Holding AG (CH) 2001-10-31 EP disclosed
EP-0120528-A1 Detergent compositions UNILEVER N.V. (NL) 1984-10-03 EP disclosed
US-4375416-A TERTIARY AMINE, SMECTITES, ANIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1983-03-01 US disclosed
EP-0011340-B1 DETERGENT COMPOSITION HAVING TEXTILE SOFTENING PROPERTIES THE PROCTER & GAMBLE COMPANY (US) 1982-11-24 EP disclosed
US-4338204-A Detergent softener containing anionic, amine, and water soluble cationic THE PROCTER & GAMBLE COMPANY (US) 1982-07-06 US disclosed
US-4294710-A ANIONIC SURFACTANTS, BUILDER SALTS, ALKYLAMINES OR IMIDAZOLES THE PROCTER & GAMBLE COMPANY (US) 1981-10-13 US disclosed
EP-0026528-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1981-04-08 EP disclosed
EP-0026529-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1981-04-08 EP disclosed
EP-0023367-A1 Detergent composition having textile softening property THE PROCTER & GAMBLE COMPANY (US) 1981-02-04 EP disclosed
EP-0011340-A1 Detergent composition having textile softening properties THE PROCTER & GAMBLE COMPANY (US) 1980-05-28 EP disclosed
US-4130498-A NONIONIC SURFACTANT, BUILDER AND EXTENDER, UREA-FORMALDEHYDE RESIN CIBA-GEIGY AG (CH) 1978-12-19 US disclosed