SCHEMBL8612737

SCHEMBL8612737

Nc1c(C=Cc2ccccc2)cccc1-c1ccnnn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.39
NFE2L2 Q16236 3/20 0.36
CYP19A1 P11511 2/20 0.36
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
TRPA1 O75762 2/20 0.36
GRM4 Q14833 3/20 0.36
NPC1 O15118 2/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HDAC6 Q9UBN7 1/20 0.34
SLC2A1 P11166 1/20 0.34
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30785927 1.00 DHFR (0.39) DHFRNFE2L2CYP19A1MAOAMAOB
SCHEMBL30677882 1.00 DHFR (0.39) DHFRNFE2L2CYP19A1MAOAMAOB
SCHEMBL5490455 0.89 DHFR (0.36) DHFRNFE2L2CYP19A1MAOAMAOB
SCHEMBL1136448 0.87 NFE2L2 (0.41) DHFRNFE2L2MAOBTRPA1NPC1
SCHEMBL1536251 0.87 NFE2L2 (0.41) DHFRNFE2L2MAOBTRPA1NPC1
SCHEMBL1012568 0.84 NFE2L2 (0.37) DHFRNFE2L2MAOBTRPA1KDM4E
SCHEMBL11499911 0.84 DHFR (0.35) DHFRNFE2L2CYP19A1MAOAMAOB
SCHEMBL3113210 0.80 SLC2A1 (0.34) DHFRNFE2L2CYP19A1MAOAMAOB
SCHEMBL9774338 0.79 DHFR (0.36) DHFRCYP19A1MAOAMAOBGRM4
SCHEMBL6323747 0.78 NFE2L2 (0.31) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116429738-A Composition for blood detection and detection method thereof 张铸业 2023-07-14 CN claimed
CN-114058137-B Weather-resistant antistatic transparent PVC/PMMA alloy material and preparation method thereof 广东天雄新材料科技股份有限公司 2023-04-11 CN claimed
CN-113717117-A Process for synthesizing fluorescent whitening agent under assistance of ultrasonic waves 浙江宏达化学制品有限公司 2021-11-30 CN claimed
CN-113463368-A CXT liquid fluorescent whitening agent and preparation method thereof 浙江宏达化学制品有限公司 2021-10-01 CN claimed
CN-112252059-A Natural color cotton deepening and color fixing after-finishing agent 浙江理工大学 2021-01-22 CN claimed
EP-0462793-B1 Surfactant ion pair fluorescent whitener compositions CLOROX CO (US) 1997-11-05 EP claimed
EP-0462793-A2 Surfactant ion pair fluorescent whitener compositions The Clorox Company (US) 1991-12-27 EP claimed
US-5057236-A Stable to hypochlorite bleach THE CLOROX COMPANY (US) 1991-10-15 US claimed
CN-119463848-A Nanometer TiO2Preparation method of composite fluorescent whitening agent 浙江弘毅化学有限公司 2025-02-18 CN disclosed
CN-116429738-A Composition for blood detection and detection method thereof 张铸业 2023-07-14 CN disclosed
CN-114058137-B Weather-resistant antistatic transparent PVC/PMMA alloy material and preparation method thereof 广东天雄新材料科技股份有限公司 2023-04-11 CN disclosed
CN-115029956-A Card paper and preparation method thereof 万国纸业太阳白卡纸有限公司 2022-09-09 CN disclosed
CN-114775092-A Preparation method of multifunctional composite fiber 浙江康必达纺织科技有限公司 2022-07-22 CN disclosed
CN-114058137-A Weather-resistant antistatic transparent PVC/PMMA alloy material and preparation method thereof 广东天雄新材料科技股份有限公司 2022-02-18 CN disclosed
CN-1061430-A The detergent composition that contains polyhydroxy fatty acid amide and alkyl alkoxylated suifate PROCTER & GAMBLE (US) 1992-05-27 CN disclosed
CN-1061244-A Polyhydroxy fatty acid amide in the polycarboxylate built detergent PROCTER & GAMBLE (US) 1992-05-20 CN disclosed
CN-1061242-A Contain the polyhydroxy fatty acid amide in the detergent composition of dirt release agent PROCTER & GAMBLE (US) 1992-05-20 CN disclosed
CN-1061041-A The detergent composition that contains polyhydroxy fatty acid amide and alkyl sulfonate surfactants PROCTER & GAMBLE (US) 1992-05-13 CN disclosed
EP-0462793-A2 Surfactant ion pair fluorescent whitener compositions The Clorox Company (US) 1991-12-27 EP disclosed
US-5057236-A Stable to hypochlorite bleach THE CLOROX COMPANY (US) 1991-10-15 US disclosed