Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Methyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070315 | 0.95 | — | — | |
| SCHEMBL25599 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL246838 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL8596055 | 0.94 | CA2 (0.58) | — | |
| SCHEMBL105 | 0.94 | — | — | |
| SCHEMBL128169 | 0.94 | — | — | |
| SCHEMBL15109974 | 0.94 | — | — | |
| SCHEMBL8729088 | 0.89 | — | — | |
| SCHEMBL21641627 | 0.89 | CA2 (0.54) | — | |
| SCHEMBL8541710 | 0.89 | CA2 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271301-A | Preparation method of enggliflozin | 甘李药业股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-117209500-A | SHP2 inhibitor, crystal form thereof, preparation method and application thereof | 上海凌达生物医药有限公司 | 2023-12-12 | — | — | CN | claimed |
| WO-2023143576-A1 | CRYSTALLINE FORM OR AMORPHOUS FORM OF MACROCYCLIC COMPOUND OR SALT OR SOLVATE THEREOF | 苏州亚盛药业有限公司 | 2023-08-03 | — | — | WO | claimed |
| CN-113248464-B | Synthesis method of C-glycoside derivatives | 北京惠之衡生物科技有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113248464-A | Synthesis method of C-glycoside derivatives | 北京惠之衡生物科技有限公司 | 2021-08-13 | — | — | CN | claimed |
| CN-113045525-A | Preparation method of C-glucoside derivative and preparation thereof | 北京惠之衡生物科技有限公司 | 2021-06-29 | — | — | CN | claimed |
| US-10954246-B2 | Compound of EOC315 Mod.I crystal form and preparation method thereof | Taizhou Eoc Pharma Co., Ltd. (CN) | 2021-03-23 | — | — | US | claimed |
| CN-109553609-A | A kind of preparation method of canagliflozin | 北大方正集团有限公司 | 2019-04-02 | — | — | CN | claimed |
| US-9914724-B2 | C-aryl glycosid derivatives, pharmaceutical composition, preparation process and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-03-13 | — | — | US | claimed |
| EP-3133071-A1 | C-ARYL INDICAN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR AND USES THEREOF | Shanghai De Novo Pharmatech Co Ltd. (CN) | 2017-02-22 | — | — | EP | claimed |
| US-20170037038-A1 | C- ARYL GLYCOSID DERIVATIVES, PHARMACEUTICAL COMPOSITION, PREPARATION PROCESS AND USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO. LTD. (CN) | 2017-02-09 | — | — | US | claimed |
| CN-104262280-B | A kind of preparation method of linezolid | 山东华生化学股份有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-105753910-A | Preparation method of canagliflozin intermediate | 康普药业股份有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-100582749-C | Method for assaying 3,5-substituted oxazolidones compound content | SICHUAN BEILIKE BIOTECHNIC CO LTD | 2010-01-20 | — | — | CN | claimed |
| CN-101021512-A | Method for detecting content of 3,5-substituted oxaolidones compound | SICHUAN BEILIKE BIOTECHNICS CO (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-101021487-A | Method for assaying 3,5-substituted oxazolidones compound content | SICHUAN BEILIKE BIOTECHNIC CO (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-101021511-A | Method for detecting purity of 3,5 substituted oxazolidones compound | SICHUAN BEILIKE BIOTECHNIC CO (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-101019825-A | Process of dissolving 3,5-substituted oxazolidone | SICHUAN BEILIKE BIOTECHNOLOGY (CN) | 2007-08-22 | — | — | CN | claimed |
| WO-2024254599-A1 | HPGD INHIBITORS AND USES THEREOF | NIMBUS DISCOVERY, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| EP-0080085-A1 | Producing methyl ethers from branched monoolefins | ALLIED CORPORATION (US) | 1983-06-01 | — | — | EP | disclosed |