SCHEMBL5490742

SCHEMBL5490742

O=Cc1ccc(-c2cc(C=O)ccc2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
CYP2A6 P11509 1/20 0.50
DRD1 P21728 4/20 0.46
DRD2 P14416 1/20 0.45
DRD4 P21917 1/20 0.45
DRD5 P21918 1/20 0.45
DRD3 P35462 1/20 0.45
IP6K1 Q92551 1/20 0.44
TRIM24 O15164 1/20 0.43
TRIM33 Q9UPN9 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 1/20 0.40
ELANE P08246 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
PELI1 Q96FA3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29671482 1.00 ALDH1A1 (0.50) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL35967 0.96 ALDH1A1 (0.48) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL28797144 0.92 IP6K1 (0.45) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL29693643 0.89 ALDH1A1 (0.46) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL28755065 0.89 TRIM24 (0.49) ALDH1A1CYP2A6DRD1IP6K1TRIM24
Benzaldehyde SCHEMBL28412466 0.88 ALDH1A1 (0.56) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL35966 0.87 ALDH1A1 (0.59) ALDH1A1CYP2A6DRD1DRD2DRD4
Hydrogen Sulfide SCHEMBL27896687 0.85 ALDH1A1 (0.56) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL30866160 0.85 ALDH1A1 (0.44) ALDH1A1CYP2A6DRD1DRD2DRD4
SCHEMBL16381822 0.83 ALDH1A1 (0.54) ALDH1A1CYP2A6DRD1DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2559720-A1 CROSSLINKED COMPOSITION Daicel Corporation (JP) 2013-02-20 EP disclosed
US-20130026458-A1 CROSSLINKABLE COMPOSITION DAICEL CORPORATION (JP) 2013-01-31 US disclosed
JP-2007261991-A METHOD FOR PRODUCING 4,4\"-DIFORMYLTERPHENYLS MITSUBISHI GAS CHEM CO INC 2007-10-11 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026458-A1 CROSSLINKABLE COMPOSITION DDC, ODC1, SRM ALDH1A1 3341/4885CYP2A6 4063/4885DRD1 1252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.