SCHEMBL5491128

SCHEMBL5491128

CCC(C)C(NC(=O)C(C)N)C(=O)C1NCCS1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
ENPEP Q07075 9/20 0.32
XIAP P98170 1/20 0.31
DPP4 P27487 2/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP7 Q9UHL4 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491123 1.00 L3MBTL1 (0.33) L3MBTL1ENPEPXIAPDPP4DPP8
SCHEMBL7056083 0.91 DPP4 (0.35) L3MBTL1ENPEPDPP4DPP8DPP7
SCHEMBL5493827 0.87 DPP4 (0.33) DPP4
SCHEMBL5493822 0.87 DPP4 (0.33) DPP4
SCHEMBL5496797 0.85 L3MBTL1 (0.33) L3MBTL1ALDH1A1
SCHEMBL5496795 0.85 L3MBTL1 (0.33) L3MBTL1ALDH1A1
SCHEMBL353690 0.79 DPP4 (0.41) DPP4DPP8DPP7
SCHEMBL1445688 0.79 DPP4 (0.41) DPP4DPP8DPP7
SCHEMBL354706 0.79 DPP4 (0.41) DPP4DPP8DPP7
SCHEMBL5494046 0.79 DPP7 (0.44) L3MBTL1DPP7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7166579-B2 Prodrugs of DP IV-inhibitors PROSIDION LIMITED (GB) 2007-01-23 US claimed