Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491128 | 0.91 | L3MBTL1 (0.33) | DPP4DPP8DPP7L3MBTL1ENPEP | |
| SCHEMBL5491123 | 0.91 | L3MBTL1 (0.33) | DPP4DPP8DPP7L3MBTL1ENPEP | |
| SCHEMBL353690 | 0.84 | DPP4 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL354706 | 0.84 | DPP4 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1445688 | 0.84 | DPP4 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL5496797 | 0.84 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL5496795 | 0.84 | L3MBTL1 (0.33) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5706355 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL5079153 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL27529254 | 0.83 | DPP4 (0.40) | DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215207-B1 | Organic Salts of isoleucyl-thiazolidine and -pyrrolidine and their use as dipeptidylpeptidase inhibitors | PROBIODRUG AG (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-1215207-A3 | Salts of isoleucyl-thiazolidine and -pyrrolidine and their use as dipeptidylpeptidase inhibitors | Probiodrug AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| EP-1215207-A2 | Salts of isoleucyl-thiazolidine and -pyrrolidine and their use as dipeptidylpeptidase inhibitors | Probiodrug AG (DE) | 2002-06-19 | — | — | EP | disclosed |