Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HLCS | P50747 | 6/20 | 0.65 |
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771649 | 0.90 | HLCS (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL93446 | 0.90 | HLCS (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5599921 | 0.90 | HLCS (0.76) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7998361 | 0.87 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL15142513 | 0.87 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3800590 | 0.87 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7233545 | 0.86 | TDP1 (0.90) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL479231 | 0.85 | HLCS (0.82) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL17830117 | 0.85 | HLCS (0.82) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10140318 | 0.84 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189692-B2 | Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2007-03-13 | — | — | US | disclosed |
| US-20030069175-A1 | Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same | BAB ITAI (IL) | 2003-04-10 | — | — | US | disclosed |
| US-6479460-B1 | PSEUDOPEPTIDIC OSTEOGENIC GROWTH POLYPEPTIDE | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2002-11-12 | — | — | US | disclosed |
| EP-0967989-A1 | SYNTHETIC PEPTIDES AND PSEUDOPEPTIDES HAVING OSTEOGENIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-01-05 | — | — | EP | disclosed |
| EP-0967989-A4 | SYNTHETIC PEPTIDES AND PSEUDOPEPTIDES HAVING OSTEOGENIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | YISSUM RES DEV CO (IL) | 2000-01-05 | — | — | EP | disclosed |
| WO-1997032594-A1 | SYNTHETIC PEPTIDES AND PSEUDOPEPTIDES HAVING OSTEOGENIC ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 1997-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069175-A1 | Synthetic peptides and pseudopeptides having osteogenic activity and pharmaceutical compositions containing the same | FIBP, SOST, BMP2 | TDP1 3645/4885MEN1 2709/4885ABL1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.